TY - JOUR AU - Krusche, Benjamin AU - Ottone, Cristina AU - Clements, Melanie P AU - Johnstone, Ewan R AU - Goetsch, Katrin AU - Lieven, Huang AU - Mota, Silvia G AU - Singh, Poonam AU - Khadayate, Sanjay AU - Ashraf, Azhaar AU - Davies, Timothy AU - Pollard, Steven M AU - De Paola, Vincenzo AU - Roncaroli, Federico AU - Martinez Torrecuadrada, Jorge Luis AU - Bertone, Paul AU - Parrinello, Simona PY - 2016 DO - 10.7554/eLife.14845 SN - 2050-084X UR - http://hdl.handle.net/20.500.12105/7888 AB - Glioblastomas (GBM) are aggressive and therapy-resistant brain tumours, which contain a subpopulation of tumour-propagating glioblastoma stem-like cells (GSC) thought to drive progression and recurrence. Diffuse invasion of the brain parenchyma,... LA - eng PB - eLife Sciences Publications KW - Eph/ephrin KW - GBM KW - Cancer biology KW - Cancer stem cells KW - Cell biology KW - Human KW - Nouse KW - Perivascular invasion KW - Animals KW - Ephrin-B2 KW - Glioblastoma KW - Heterografts KW - Humans KW - Intravital Microscopy KW - Mice KW - Neoplastic Stem Cells KW - Cell Movement KW - Cell Proliferation TI - EphrinB2 drives perivascular invasion and proliferation of glioblastoma stem-like cells TY - journal article ER -