TY  - JOUR
AU  - Murga, Matilde
AU  - Campaner, Stefano
AU  - Lopez-Contreras, Andres J
AU  - Toledo, Luis I
AU  - Soria, Rebeca
AU  - Montaña, Maria F
AU  - Artista, Luana D'
AU  - Schleker, Thomas
AU  - Guerra, Carmen
AU  - Garcia, Elena
AU  - Barbacid, Mariano
AU  - Hidalgo, Manuel
AU  - Amati, Bruno
AU  - Fernandez-Capetillo, Oscar
PY  - 2011
DO  - 10.1038/nsmb.2189
UR  - http://hdl.handle.net/20.500.12105/17951
AB  - Oncogene-induced replicative stress activates an Atr- and Chk1-dependent response, which has been proposed to be widespread in tumors. We explored whether the presence of replicative stress could be exploited for the selective elimination of cancer...
LA  - eng
PB  - Nature Publishing Group
KW  - Stress, Physiological
KW  - Adenocarcinoma
KW  - Animals
KW  - Antineoplastic Agents
KW  - Apoptosis
KW  - Ataxia Telangiectasia Mutated Proteins
KW  - Cell Cycle Proteins
KW  - Checkpoint Kinase 1
KW  - DNA Damage
KW  - Lymphoma
KW  - Mice
KW  - Pancreatic Neoplasms
KW  - Protein Kinase Inhibitors
KW  - Protein Kinases
KW  - Protein Serine-Threonine Kinases
KW  - Proto-Oncogene Proteins c-myc
TI  - Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors.
TY  - journal article
ER  -