TY - JOUR AU - Mira, Emilia AU - Carmona-Rodriguez, Lorena AU - Perez-Villamil, Beatriz AU - Casas, Josefina AU - Fernández-Aceñero, María Jesús AU - Martinez-Rey, Diego AU - Martin-Gonzalez, Paula AU - Heras-Murillo, Ignacio AU - Paz-Cabezas, Mateo AU - Tardaguilal, Manuel AU - Oury, Tim D. AU - Martin-Puig, Silvia AU - Ana Lacalle, Rosa AU - Fabrias, Gemma AU - Diaz-Rubio, Eduardo AU - Manes, Santos PY - 2018 DO - 10.1038/s41467-018-03079-1 SN - 2041-1723 UR - http://hdl.handle.net/20.500.12105/6688 AB - One drawback of chemotherapy is poor drug delivery to tumor cells, due in part to hyper-permeability of the tumor vasculature. Extracellular superoxide dismutase (SOD3) is an antioxidant enzyme usually repressed in the tumor milieu. Here we show that... LA - eng PB - Nature Publishing Group TI - SOD3 improves the tumor response to chemotherapy by stabilizing endothelial HIF-2 alpha TY - journal article ER -