TY - GEN AU - Sánchez-Molina, Sara AU - Oliva-Martinez, Jose Luis AU - Garcia-Vargas, Susana AU - Valls, Ester AU - Rojas-Cabañeros, Jose Maria AU - Martínez-Balbás, Marian A PY - 2006 DO - 10.1042/BJ20060052 SN - 0264-6021 UR - https://hdl.handle.net/20.500.12105/26127 AB - The CBP [CREB (cAMP-response-element-binding protein)-binding protein]/p300 acetyltransferases function as transcriptional co-activators and play critical roles in cell differentiation and proliferation. Accumulating evidence shows that alterations of... LA - eng PB - Portland Press KW - Acetylation KW - cAMP-response-element-binding-protein-binding protein/p300 (CBP/p300) KW - Histone acetyltransferase activity (HAT activity) KW - Murine double minute 2 (Mdm2) KW - NIH 3T3 cell KW - Ras pathway KW - Animals KW - Cell Cycle Proteins KW - Enzyme Activation KW - Gene Expression KW - Histone Acetyltransferases KW - Mice KW - NIH 3T3 Cells KW - Platelet-Derived Growth Factor KW - Proteasome Endopeptidase Complex KW - Proto-Oncogene Proteins c-mdm2 KW - Signal Transduction KW - Transcription Factors KW - Ubiquitins KW - Valine KW - p300-CBP Transcription Factors KW - ras Proteins TI - The histone acetyltransferases CBP/p300 are degraded in NIH 3T3 cells by activation of Ras signalling pathway. TY - research article ER -