TY - JOUR AU - Roldán, Esther AU - Fuxa, Martin AU - Chong, Winnie AU - Martinez Garcia, Maria Dolores AU - Novatchkova, Maria AU - Busslinger, Meinrad AU - Skok, Jane A PY - 2005 DO - 10.1038/ni1150 SN - 1529-2908 UR - http://hdl.handle.net/20.500.12105/17405 AB - Allelic exclusion of immunoglobulin genes ensures the expression of a single antibody molecule in B cells through mostly unknown mechanisms. Large-scale contraction of the immunoglobulin heavy-chain (Igh) locus facilitates rearrangements between Igh... LA - eng PB - Nature Publishing Group KW - Alleles KW - Animals KW - Gene Rearrangement, B-Lymphocyte, Heavy Chain KW - Immunoglobulin Heavy Chains KW - Immunoglobulin Variable Region KW - Mice KW - Mice, Transgenic TI - Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene. TY - journal article ER -