TY - JOUR AU - Rivera-Torres, Jose AU - Acin-Perez, Rebeca AU - Cabezas-Sánchez, Pablo AU - Osorio, Fernando G AU - Gonzalez-Gomez, Cristina AU - Megias Vazquez, Diego AU - Cámara, Carmen AU - López-Otín, Carlos AU - Enriquez, Jose Antonio AU - Luque-García, José L AU - Andres, Vicente PY - 2013 DO - 10.1016/j.jprot.2013.08.008 SN - 1874-3919 UR - http://hdl.handle.net/20.500.12105/7755 AB - UNLABELLED: Hutchinson-Gilford progeria syndrome (HGPS) is a rare segmental premature aging disorder that recapitulates some biological and physical aspects of physiological aging. The disease is caused by a sporadic dominant mutation in the LMNA gene... LA - eng PB - Elsevier KW - ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1 KW - ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit KW - ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 KW - ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide KW - ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide KW - ATP5A1 KW - ATP5B KW - ATP5C1 KW - ATP5F1 KW - ATP5O KW - Accelerated aging KW - COX KW - CS KW - ENO2 KW - FTI KW - FpSDH KW - HGPS KW - Hutchinson–Gilford progeria syndrome KW - Lamin A KW - MAF KW - Mitochondrial dysfunction KW - Molecular biology of aging KW - OXPHOS KW - PKM KW - Progerin KW - SILAC KW - Zmpste24 KW - citrate synthase KW - cytochrome c oxidase KW - eIF2 KW - eIF4 KW - Enolase 2 KW - Eukaryotic translation initiation factor 2 KW - Eukaryotic translation initiation factor 4 KW - Farnesyltransferase inhibitor KW - Flavoprotein subunit of succinate dehydrogenase KW - mTOR KW - Mammalian target of rapamycin KW - Mouse adult fibroblast KW - Oxidative phosphorylation KW - p70S6K KW - Pyruvate kinase, muscle KW - Ribosomal protein S6 kinase, 70kDa, polypeptide 1 KW - Stable isotope labeling with amino acids in cell culture KW - Zinc metalloproteinase STE24 homolog TI - Identification of mitochondrial dysfunction in Hutchinson-Gilford progeria syndrome through use of stable isotope labeling with amino acids in cell culture TY - journal article ER -