TY - GEN AU - Navas, Francisco AU - Chocarro-Calvo, Ana AU - Iglesias-Hernandez, Patricia AU - Iglesias-Hernandez, Patricia AU - Fernández-García, Paloma AU - Morales, Victoria AU - García-Martínez, José Manuel AU - Sanz, Raúl AU - De la Vieja, Antonio AU - García-Jiménez, Custodia AU - García-Muñoz, Rafael A PY - 2024 DO - 10.1021/acs.jmedchem.3c02393 SN - 0022-2623 UR - https://hdl.handle.net/20.500.12105/25544 AB - We report two novel prodrug Pt(IV) complexes with bis-organosilane ligands in axial positions: -dichloro(diamine)--[3-(triethoxysilyl)propylcarbamate]platinum(IV) (Pt(IV)-biSi-1) and -dichloro(diisopropylamine)--[3-(triethoxysilyl) propyl... LA - eng PB - ACS Publications KW - Animals KW - Antineoplastic Agents KW - Cell Line, Tumor KW - Drug Screening Assays, Antitumor KW - HT29 Cells KW - Humans KW - Ligands KW - Mice KW - Organoplatinum Compounds KW - Prodrugs KW - Silanes KW - Structure-Activity Relationship TI - Promising Anticancer Prodrugs Based on Pt(IV) Complexes with Bis-organosilane Ligands in Axial Positions TY - research article ER -