TY  - GEN
AU  - Ferrandiz-Avellano, Maria-Jose
AU  - Martin-Galiano, Antonio Javier
AU  - Arnanz, Cristina
AU  - Zimmerman, T
AU  - de la Campa, Adela G
PY  - 2016
DO  - 10.1128/AAC.02299-15
SN  - 0066-4804
UR  - http://hdl.handle.net/20.500.12105/8594
AB  - We studied the transcriptomic response of Streptococcus pneumoniae to the fluoroquinolone moxifloxacin at a concentration that inhibits DNA gyrase. Treatment of the wild-type strain R6, at a concentration of 10× the MIC, triggered a response involving...
LA  - eng
PB  - American Society for Microbiology (ASM)
KW  - Acetyl-CoA Carboxylase
KW  - Acetyltransferases
KW  - Anti-Bacterial Agents
KW  - Bacterial Proteins
KW  - DNA Topoisomerase IV
KW  - Drug Resistance, Multiple, Bacterial
KW  - Fluoroquinolones
KW  - Fructosephosphates
KW  - Gene Deletion
KW  - Gene Expression Profiling
KW  - Gene Ontology
KW  - Glycolysis
KW  - Hydrogen Peroxide
KW  - Iron
KW  - Levofloxacin
KW  - Microbial Sensitivity Tests
KW  - Molecular Sequence Annotation
KW  - Moxifloxacin
KW  - Oxidative Stress
KW  - Pyruvate Oxidase
KW  - Pyruvic Acid
KW  - Streptococcus pneumoniae
KW  - Transcription, Genetic
KW  - Gene Expression Regulation, Bacterial
TI  - Reactive Oxygen Species Contribute to the Bactericidal Effects of the Fluoroquinolone Moxifloxacin in Streptococcus pneumoniae
TY  - research article
ER  -