TY  - GEN
AU  - Calero, Olga
AU  - Bullido, María Jesús
AU  - Clarimón, Jordi
AU  - Frank-García, Ana
AU  - Martinez-Martin, Pablo
AU  - Lleó, Alberto
AU  - Rey, María Jesús
AU  - Sastre, Isabel
AU  - Rábano, Alberto
AU  - Pedro-Cuesta, Jesus de
AU  - Ferrer, Isidro
AU  - Calero, Miguel
PY  - 2012
DO  - 10.1371/journal.pone.0043926
SN  - 1932-6203
UR  - http://hdl.handle.net/20.500.12105/6839
AB  - The β site APP cleaving enzyme 1 (BACE1) is the rate-limiting β-secretase enzyme in the amyloidogenic processing of APP and Aβ formation, and therefore it has a prominent role in Alzheimer's disease (AD) pathology. Recent evidence suggests that the...
LA  - eng
PB  - Public Library of Science (PLOS)
KW  - Aged
KW  - Amyloid Precursor Protein Secretases
KW  - Aspartic Acid Endopeptidases
KW  - Case-Control Studies
KW  - Codon
KW  - Creutzfeldt-Jakob Syndrome
KW  - Genetic Predisposition to Disease
KW  - Humans
KW  - Polymorphism, Single Nucleotide
TI  - A common BACE1 polymorphism is a risk factor for sporadic Creutzfeldt-Jakob disease
TY  - research article
ER  -