TY  - JOUR
AU  - Grunt, Thomas W
AU  - Slany, Astrid
AU  - Semkova, Mariya
AU  - López-Rodríguez, María Luz
AU  - Wuczkowski, Michael
AU  - Wagner, Renate
AU  - Gerner, Christopher
AU  - Stübiger, Gerald
AU  - Colomer, Ramón
PY  - 2020
DO  - 10.1038/s41598-020-71491-z
UR  - http://hdl.handle.net/20.500.12105/11094
AB  - Fatty-acid(FA)-synthase(FASN) is a druggable lipogenic oncoprotein whose blockade causes metabolic disruption. Whether drug-induced metabolic perturbation is essential for anticancer drug-action, or is just a secondary-maybe even a defence response-is...
LA  - eng
PB  - Nature Publishing Group
TI  - Membrane disruption, but not metabolic rewiring, is the key mechanism of anticancer-action of FASN-inhibitors: a multi-omics analysis in ovarian cancer.
TY  - journal article
ER  -