TY - JOUR AU - Ramos-Sevillano, Elisa AU - Moscoso, Miriam AU - García, Pedro AU - García, Ernesto AU - Yuste, Jose Enrique PY - 2011 DO - 10.1371/journal.pone.0023626 SN - 1932-6203 UR - http://hdl.handle.net/20.500.12105/6937 AB - BACKGROUND: Streptococcus pneumoniae is a common colonizer of the human nasopharynx and one of the major pathogens causing invasive disease worldwide. Dissection of the molecular pathways responsible for colonization, invasion, and evasion of the... LA - eng PB - Public Library of Science (PLOS) KW - Adult KW - Animals KW - Bacterial Adhesion KW - Cell Membrane KW - Cell Wall KW - Colony Count, Microbial KW - Complement C3b KW - Disease Models, Animal KW - Humans KW - Hydrolases KW - Macrophages, Alveolar KW - Male KW - Membrane Proteins KW - Mice KW - Mice, Inbred C57BL KW - Mutation KW - N-Acetylmuramoyl-L-alanine Amidase KW - Nasopharynx KW - Neutrophils KW - Phagocytosis KW - Pneumococcal Infections KW - Sepsis KW - Streptococcus pneumoniae TI - Nasopharyngeal colonization and invasive disease are enhanced by the cell wall hydrolases LytB and LytC of Streptococcus pneumoniae TY - journal article ER -