TY - GEN AU - Carrato, A AU - Benavides, M AU - Massuti, B AU - Ferreiro-Monteagudo, R AU - Garcia Alfonso, Pilar AU - Falcó, Esther AU - Reboredo, M AU - Cano, T AU - Gallego, Javier AU - Vieitez, JM AU - Layos, L AU - Salud, A AU - Polo, E AU - Dotor, Emma AU - Duran-Ogalla, G AU - Rodriguez-Garrote, M AU - Calvo, A AU - Grande, E AU - Aranda, E PY - 2019 DO - 10.1186/s12885-019-5753-7 SN - 1471-2407 UR - https://hdl.handle.net/20.500.12105/22655 AB - Background: Treatment of frail patients with advanced colorectal cancer (CRC) is controversial. This pilot phase II trial aimed to assess the efficacy and safety of regorafenib when administered in first-line to frail patients with advanced CRC.... LA - eng PB - BioMed Central (BMC) KW - Regorafenib KW - Colorectal cancer KW - Monotherapy KW - First-line KW - Frail patients KW - Elderly TI - First-line single-agent regorafenib in frail patients with metastatic colorectal cancer: a pilot phase II study of the Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) TY - research article ER -