TY - JOUR AU - Gonzalez, Jose M AU - Pla, Davinia AU - Perez-Sala, Dolores AU - Andres, Vicente PY - 2011 DO - 10.2741/216 UR - http://hdl.handle.net/20.500.12105/7658 AB - Lamin A and lamin C (A-type lamins, both encoded by the LMNA gene) are major components of the mammalian nuclear lamina, a complex proteinaceous structure that acts as a scaffold for protein complexes that regulate nuclear structure and function.... LA - eng KW - Animals KW - Contracture KW - Farnesyltranstransferase KW - Genetic Therapy KW - Humans KW - Lamin Type A KW - Mice KW - Models, Biological KW - Nuclear Lamina KW - Nuclear Proteins KW - Progeria KW - Protein Precursors KW - Skin Abnormalities TI - A-type lamins and Hutchinson-Gilford progeria syndrome: pathogenesis and therapy TY - journal article ER -