TY  - JOUR
AU  - Costa-Silva, Bruno
AU  - Aiello, Nicole M
AU  - Ocean, Allyson J
AU  - Singh, Swarnima
AU  - Zhang, Haiying
AU  - Thakur, Basant Kumar
AU  - Becker, Annette
AU  - Hoshino, Ayuko
AU  - Mark, Milica Tešić
AU  - Molina, Henrik
AU  - Xiang, Jenny
AU  - Zhang, Tuo
AU  - Theilen, Till-Martin
AU  - García-Santos, Guillermo
AU  - Williams, Caitlin
AU  - Ararso, Yonathan
AU  - Huang, Yujie
AU  - Rodrigues, Gonçalo
AU  - Shen, Tang-Long
AU  - Labori, Knut Jørgen
AU  - Lothe, Inger Marie Bowitz
AU  - Kure, Elin H
AU  - Hernandez, Jonathan
AU  - Doussot, Alexandre
AU  - Ebbesen, Saya H
AU  - Grandgenett, Paul M
AU  - Hollingsworth, Michael A
AU  - Jain, Maneesh
AU  - Mallya, Kavita
AU  - Batra, Surinder K
AU  - Jarnagin, William R
AU  - Schwartz, Robert E
AU  - Matei, Irina
AU  - Peinado, Héctor
AU  - Stanger, Ben Z
AU  - Bromberg, Jacqueline
AU  - Lyden, David
PY  - 2015
DO  - 10.1038/ncb3169
UR  - http://hdl.handle.net/20.500.12105/17975
AB  - Pancreatic ductal adenocarcinomas (PDACs) are highly metastatic with poor prognosis, mainly due to delayed detection. We hypothesized that intercellular communication is critical for metastatic progression. Here, we show that PDAC-derived exosomes...
LA  - eng
PB  - Nature Publishing Group
KW  - Animals
KW  - Base Sequence
KW  - Bone Marrow Cells
KW  - Carcinoma, Pancreatic Ductal
KW  - Cell Line, Tumor
KW  - Cell Movement
KW  - Exosomes
KW  - Female
KW  - Fibronectins
KW  - Gene Expression Regulation, Neoplastic
KW  - Hepatic Stellate Cells
KW  - Humans
KW  - Liver
KW  - Liver Neoplasms
KW  - Macrophage Migration-Inhibitory Factors
KW  - Macrophages
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mice, Knockout
KW  - Pancreatic Neoplasms
KW  - Precancerous Conditions
KW  - RNA Interference
KW  - RNA, Small Interfering
KW  - Sequence Analysis, RNA
KW  - Signal Transduction
KW  - Transforming Growth Factor beta
TI  - Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver.
TY  - journal article
ER  -