TY - JOUR AU - Ho, Ya-Hsuan AU - Del Toro, Raquel AU - Rivera-Torres, Jose AU - Rak, Justyna AU - Korn, Claudia AU - Garcia-Garcia, Andres AU - Macías, David AU - Gonzalez-Gomez, Cristina AU - del Monte, Alberto AU - Wittner, Monika AU - Waller, Amie K AU - Foster, Holly R AU - López-Otín, Carlos AU - Johnson, Randall S AU - Nerlov, Claus AU - Ghevaert, Cedric AU - Vainchenker, William AU - Louache, Fawzia AU - Andres, Vicente AU - Mendez-Ferrer, Simon PY - 2019 DO - 10.1016/j.stem.2019.06.007 SN - 19345909 UR - http://hdl.handle.net/20.500.12105/8331 AB - Hematopoietic stem cells (HSCs) residing in the bone marrow (BM) accumulate during aging but are functionally impaired. However, the role of HSC-intrinsic and -extrinsic aging mechanisms remains debated. Megakaryocytes promote quiescence of... LA - eng PB - Elsevier KW - Hutchinson-Gilford progeria KW - Aging KW - Hematopoietic stem cell KW - Lymphoid KW - Microenvironment KW - Myeloid KW - Niche TI - Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging TY - journal article ER -