TY - GEN AU - Nadezhdin, Kirill D AU - Garcia-Carpio, Irmina AU - Goncharuk, Sergey A AU - Mineev, Konstantin S AU - Arseniev, Alexander S AU - Vilar, Marçal PY - 2016 DO - 10.1074/jbc.M116.723585 SN - 0021-9258 UR - http://hdl.handle.net/20.500.12105/9668 AB - Dimerization of single span transmembrane receptors underlies their mechanism of activation. p75 neurotrophin receptor plays an important role in the nervous system, but the understanding of p75 activation mechanism is still incomplete. The... LA - eng PB - American Society for Biochemistry and Molecular Biology (ASBMB) KW - Dimerization KW - Neurotrophin KW - Nuclear magnetic resonance (NMR) KW - p75 neurotrophin receptor KW - Transmembrane domain KW - γ-secretase KW - Amino Acid Motifs KW - Amino Acid Sequence KW - Blotting, Western KW - Cysteine KW - HeLa Cells KW - Humans KW - Lipids KW - Magnetic Resonance Spectroscopy KW - Membrane Proteins KW - Micelles KW - Models, Molecular KW - Mutation KW - Oxidation-Reduction KW - Proteolysis KW - Receptor, Nerve Growth Factor KW - Protein Domains KW - Protein Multimerization KW - Protein Structure, Secondary TI - Structural Basis of p75 Transmembrane Domain Dimerization TY - research article ER -