TY  - GEN
AU  - Pajares, María A.
AU  - Zimmerman, Tahl
AU  - Sánchez-Gómez, Francisco J.
AU  - Ariza, Adriana
AU  - Torres, María J.
AU  - Blanca, Miguel
AU  - Cañada, F. Javier
AU  - Montañez, María I.
AU  - Pérez-Sala, Dolores
PY  - 2020
DO  - 10.3389/fphar.2020.00189
UR  - http://hdl.handle.net/20.500.12105/18010
AB  - Serum and cellular proteins are targets for the formation of adducts with the β-lactam antibiotic amoxicillin. This process could be important for the development of adverse, and in particular, allergic reactions to this antibiotic. In studies...
LA  - eng
PB  - Frontiers Media
KW  - Amoxicillin
KW  - B-lactam antibiotics
KW  - Inactivation mechanism
KW  - Redox regulation
KW  - Protein adducts
KW  - Thiol groups
KW  - Thiol-containing molecules
KW  - Bacterial growth
KW  - Amoxicilina
KW  - Beta-lactamas
KW  - Crecimiento bacteriano
KW  - Acetylcysteine
KW  - Amoxicillin
KW  - Dithiothreitol
KW  - Cefaclor
KW  - beta-Lactams
KW  - Reducing Agents
KW  - Anti-Bacterial Agents
KW  - Diketopiperazines
KW  - Hypersensitivity
KW  - Glutathione
KW  - Oxidation-Reduction
TI  - Amoxicillin Inactivation by Thiol-Catalyzed Cyclization Reduces Protein Haptenation and Antibacterial Potency
TY  - research article
ER  -