TY - JOUR AU - Campos-Iglesias, Diana AU - Fraile, Julia M AU - Bretones, Gabriel AU - Montero, Alejandro A AU - Bonzon-Kulichenko, Elena AU - Vazquez, Jesus AU - López-Otín, Carlos AU - Freije, José M P PY - 2023 DO - 10.1038/s41419-023-05600-x UR - http://hdl.handle.net/20.500.12105/16466 AB - The spindle assembly checkpoint (SAC) is an essential mechanism that ensures the accurate chromosome segregation during mitosis, thus preventing genomic instability. Deubiquitinases have emerged as key regulators of the SAC, mainly by determining the... LA - eng PB - Springer KW - M Phase Cell Cycle Checkpoints KW - Spindle Apparatus KW - Humans KW - Aneuploidy KW - Mitosis KW - Deubiquitinating Enzymes KW - Cell Cycle Proteins KW - Ubiquitin Thiolesterase TI - USP49 deubiquitinase regulates the mitotic spindle checkpoint and prevents aneuploidy. TY - journal article ER -