TY  - JOUR
AU  - Di Martino, Orsola
AU  - Ferris, Margaret A
AU  - Hadwiger, Gayla
AU  - Sarkar, Soyi
AU  - Vu, Anh
AU  - Menéndez-Gutiérrez, María P
AU  - Ricote, Mercedes
AU  - Welch, John S
PY  - 2022
DO  - 10.3324/haematol.2021.278603
UR  - http://hdl.handle.net/20.500.12105/15145
AB  - RARA and RXRA contribute to myeloid maturation in both mice and humans, and deletion of Rxra and Rxrb augments leukemic growth in mice. While defining the domains of RXRA that are required for anti-leukemic effects in murine KMT2A-MLLT3 leukemia...
LA  - eng
PB  - Fondazione Ferrata Storti
KW  - Leukemia, Myeloid, Acute
KW  - Leukemia, Promyelocytic, Acute
KW  - Retinoid X Receptor alpha
KW  - Animals
KW  - DNA-Binding Proteins
KW  - Humans
KW  - Mice
TI  - RXRA DT448/9PP generates a dominant active variant capable of inducing maturation in acute myeloid leukemia cells.
TY  - journal article
ER  -