TY  - JOUR
AU  - Peinado, Héctor
AU  - Alečković, Maša
AU  - Lavotshkin, Simon
AU  - Matei, Irina
AU  - Costa-Silva, Bruno
AU  - Moreno-Bueno, Gema
AU  - Hergueta-Redondo, Marta
AU  - Williams, Caitlin
AU  - García-Santos, Guillermo
AU  - Ghajar, Cyrus
AU  - Nitadori-Hoshino, Ayuko
AU  - Hoffman, Caitlin
AU  - Badal, Karen
AU  - Garcia, Benjamin A
AU  - Callahan, Margaret K
AU  - Yuan, Jianda
AU  - Martins, Vilma R
AU  - Skog, Johan
AU  - Kaplan, Rosandra N
AU  - Brady, Mary S
AU  - Wolchok, Jedd D
AU  - Chapman, Paul B
AU  - Kang, Yibin
AU  - Bromberg, Jacqueline
AU  - Lyden, David
PY  - 2012
DO  - 10.1038/nm.2753
UR  - http://hdl.handle.net/20.500.12105/17965
AB  - Tumor-derived exosomes are emerging mediators of tumorigenesis. We explored the function of melanoma-derived exosomes in the formation of primary tumors and metastases in mice and human subjects. Exosomes from highly metastatic melanomas increased the...
LA  - eng
PB  - Nature Publishing Group
KW  - Animals
KW  - Bone Marrow Cells
KW  - Cell Line
KW  - Exosomes
KW  - Female
KW  - Humans
KW  - Melanoma
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Phenotype
KW  - Prognosis
KW  - Proto-Oncogene Proteins c-met
KW  - Stem Cells
KW  - rab GTP-Binding Proteins
KW  - rab27 GTP-Binding Proteins
TI  - Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.
TY  - journal article
ER  -