TY - JOUR AU - Riquelme, Paloma AU - Haarer, Jan AU - Kammler, Anja AU - Walter, Lisa AU - Tomiuk, Stefan AU - Ahrens, Norbert AU - Wege, Anja K AU - Goecze, Ivan AU - Zecher, Daniel AU - Banas, Bernhard AU - Spang, Rainer AU - Fändrich, Fred AU - Lutz, Manfred B AU - Sawitzki, Birgit AU - Schlitt, Hans J AU - Ochando, Jordi AU - Geissler, Edward K AU - Hutchinson, James A PY - 2018 DO - 10.1038/s41467-018-05167-8 UR - http://hdl.handle.net/20.500.12105/10394 AB - Human regulatory macrophages (Mreg) have shown early clinical promise as a cell-based adjunct immunosuppressive therapy in solid organ transplantation. It is hypothesised that recipient CD4+ T cell responses are actively regulated through direct... LA - eng PB - Nature Publishing Group KW - Allografts KW - Animals KW - Cell Differentiation KW - Dendritic Cells KW - Forkhead Transcription Factors KW - Graft Rejection KW - Humans KW - Interleukin-10 KW - Kidney Transplantation KW - Lipopolysaccharide Receptors KW - Macrophages KW - Mice KW - Phenotype KW - Receptors, Immunologic KW - Signal Transduction KW - T-Lymphocytes, Regulatory KW - Transforming Growth Factor beta KW - Transplantation, Homologous TI - TIGIT+ iTregs elicited by human regulatory macrophages control T cell immunity. TY - journal article ER -