TY  - JOUR
AU  - Schreiber, Jadwiga
AU  - Grimbergen, Laura-Anne
AU  - Overwater, Iris
AU  - Vaart, Thijs van der
AU  - Stedehouder, Jeffrey
AU  - Schuhmacher, Alberto J
AU  - Guerra, Carmen
AU  - Kushner, Steven A
AU  - Jaarsma, Dick
AU  - Elgersma, Ype
PY  - 2017
DO  - 10.1038/s41598-017-01218-0
SN  - 2045-2322
UR  - http://hdl.handle.net/20.500.12105/7298
AB  - RASopathies, characterized by germline mutations in genes encoding proteins of the RAS-ERK signaling pathway, show overlapping phenotypes, which manifest themselves with a varying severity of intellectual disability. However, it is unclear to what...
LA  - eng
PB  - Nature Publishing Group
KW  - Animals
KW  - Brain
KW  - Cognitive Dysfunction
KW  - Costello Syndrome
KW  - Depression
KW  - Disease Models, Animal
KW  - Hypertrophy
KW  - MAP Kinase Signaling System
KW  - Mice
KW  - Neurons
KW  - Proto-Oncogene Proteins p21(ras)
KW  - Mutation, Missense
TI  - Mechanisms underlying cognitive deficits in a mouse model for Costello Syndrome are distinct from other RASopathy mouse models
TY  - journal article
ER  -