TY  - GEN
AU  - Granados-Durán, Pablo
AU  - López-Ávalos, María Dolores
AU  - Hughes, Timothy R
AU  - Johnson, Krista
AU  - Morgan, B Paul
AU  - Tamburini, Paul P
AU  - Fernández-Llebrez, Pedro
AU  - Grondona, Jesús M
PY  - 2016
DO  - 10.1186/s12974-016-0576-9
UR  - http://hdl.handle.net/20.500.12105/17140
AB  - In the rat brain, a single intracerebroventricular injection of neuraminidase from Clostridium perfringens induces ependymal detachment and death. This injury occurs before the infiltration of inflammatory blood cells; some reports implicate the...
LA  - eng
KW  - Anti-C5
KW  - Brain ventricles
KW  - C6-deficient rats
KW  - Complement system
KW  - Ependymal cells
KW  - Inflammation
KW  - Neuraminidase
KW  - Animals
KW  - Antibodies
KW  - Cells, Cultured
KW  - Cerebral Ventriculitis
KW  - Complement C3
KW  - Complement C5
KW  - Complement C6
KW  - Complement Membrane Attack Complex
KW  - Disease Models, Animal
KW  - Ependyma
KW  - Gene Expression Regulation
KW  - Injections, Intraventricular
KW  - Lectins
KW  - Male
KW  - Neuraminidase
KW  - Rats
KW  - Rats, Transgenic
KW  - Rats, Wistar
KW  - Signal Transduction
KW  - Time Factors
KW  - Vimentin
TI  - Complement system activation contributes to the ependymal damage induced by microbial neuraminidase.
TY  - research article
ER  -