TY  - JOUR
AU  - Kalisz, Mark
AU  - Bernardo, Edgar
AU  - Beucher, Anthony
AU  - Maestro, Miguel Angel
AU  - Del Pozo, Natalia
AU  - Millán, Irene
AU  - Haeberle, Lena
AU  - Schlensog, Martin
AU  - Safi, Sami Alexander
AU  - Knoefel, Wolfram Trudo
AU  - Grau, Vanessa
AU  - de Vas, Matías
AU  - Shpargel, Karl B
AU  - Vaquero, Eva
AU  - Magnuson, Terry
AU  - Ortega Jimenez, Sagrario
AU  - Esposito, Irene
AU  - Real Arribas, Francisco
AU  - Ferrer, Jorge
PY  - 2020
DO  - 10.15252/embj.2019102808
UR  - http://hdl.handle.net/20.500.12105/18193
AB  - Defects in transcriptional regulators of pancreatic exocrine differentiation have been implicated in pancreatic tumorigenesis, but the molecular mechanisms are poorly understood. The locus encoding the transcription factor HNF1A harbors susceptibility...
LA  - eng
PB  - EMBO Press
KW  - Acinar Cells
KW  - Animals
KW  - Carcinoma, Pancreatic Ductal
KW  - Epigenesis, Genetic
KW  - Gene Expression Regulation, Neoplastic
KW  - Gene Regulatory Networks
KW  - Hepatocyte Nuclear Factor 1-alpha
KW  - Histone Demethylases
KW  - Humans
KW  - Mice
KW  - Mutation
KW  - Organ Specificity
KW  - Pancreas
KW  - Pancreatic Neoplasms
TI  - HNF1A recruits KDM6A to activate differentiated acinar cell programs that suppress pancreatic cancer.
TY  - journal article
ER  -