TY - GEN AU - Rodriguez Martinez, Javier M AU - Chichón, Francisco Javier AU - Martin-Forero, Esther AU - Gonzalez-Camacho, Fernando AU - Carrascosa, José L AU - Castón, José R AU - Luque, Daniel PY - 2014 DO - 10.1371/journal.ppat.1004157 SN - 1553-7374 UR - http://hdl.handle.net/20.500.12105/6945 AB - The infectivity of rotavirus, the main causative agent of childhood diarrhea, is dependent on activation of the extracellular viral particles by trypsin-like proteases in the host intestinal lumen. This step entails proteolytic cleavage of the VP4... LA - eng PB - Public Library of Science (PLOS) KW - Animals KW - Capsid KW - Cells, Cultured KW - Diarrhea KW - Haplorhini KW - Rotavirus KW - Trypsin KW - Virion KW - Virus Attachment KW - Virus Internalization TI - New insights into rotavirus entry machinery: stabilization of rotavirus spike conformation is independent of trypsin cleavage TY - research article ER -