TY  - GEN
AU  - Orth, Martin F
AU  - Surdez, Didier
AU  - Faehling, Tobias
AU  - Ehlers, Anna C
AU  - Marchetto, Aruna
AU  - Grossetête, Sandrine
AU  - Volckmann, Richard
AU  - Zwijnenburg, Danny A
AU  - Gerke, Julia S
AU  - Zaidi, Sakina
AU  - Alonso, Javier
AU  - Sastre, Ana
AU  - Baulande, Sylvain
AU  - Sill, Martin
AU  - Cidre-Aranaz, Florencia
AU  - Ohmura, Shunya
AU  - Kirchner, Thomas
AU  - Hauck, Stefanie M
AU  - Reischl, Eva
AU  - Gymrek, Melissa
AU  - Pfister, Stefan M
AU  - Strauch, Konstantin
AU  - Koster, Jan
AU  - Delattre, Olivier
AU  - Grünewald, Thomas G P
PY  - 2022
DO  - 10.1016/j.celrep.2022.111761
UR  - http://hdl.handle.net/20.500.12105/15882
AB  - Ewing sarcoma (EwS) is characterized by EWSR1-ETS fusion transcription factors converting polymorphic GGAA microsatellites (mSats) into potent neo-enhancers. Although the paucity of additional mutations makes EwS a genuine model to study principles of...
LA  - eng
PB  - Cell Press
KW  - CP: Cancer
KW  - ChiP-seq
KW  - EWSR1-ERG
KW  - EWSR1-ETS
KW  - EWSR1-FLI1
KW  - Ewing sarcoma
KW  - Enhancer
KW  - Microsatellites
KW  - Multi-omics
KW  - Pediatric sarcoma
KW  - Tumor heterogeneity
KW  - Sarcoma, Ewing
KW  - Humans
KW  - Multiomics
KW  - Oncogenes
KW  - Cell Line
KW  - Transcription Factors
TI  - Systematic multi-omics cell line profiling uncovers principles of Ewing sarcoma fusion oncogene-mediated gene regulation
TY  - research article
ER  -