TY  - JOUR
AU  - Verdura, Sara
AU  - Cuyàs, Elisabet
AU  - Llorach-Parés, Laura
AU  - Pérez-Sánchez, Almudena
AU  - Micol, Vicente
AU  - Nonell-Canals, Alfons
AU  - Joven, Jorge
AU  - Valiente, Manuel
AU  - Sánchez-Martínez, Melchor
AU  - Bosch-Barrera, Joaquim
AU  - Menendez, Javier A
PY  - 2018
DO  - 10.1016/j.fct.2018.04.028
UR  - http://hdl.handle.net/20.500.12105/15054
AB  - We herein combined experimental and computational efforts to delineate the mechanism of action through which the flavonolignan silibinin targets STAT3. Silibinin reduced IL-6 inducible, constitutive, and acquired feedback activation of STAT3 at...
LA  - eng
PB  - Elsevier
KW  - Humans
KW  - Molecular Dynamics Simulation
KW  - STAT3 Transcription Factor
KW  - Signal Transduction
KW  - Silybin
KW  - Silymarin
TI  - Silibinin is a direct inhibitor of STAT3.
TY  - journal article
ER  -