TY  - GEN
AU  - López-Nieva, Pilar
AU  - Fernandez-Navarro, Pablo L
AU  - Vaquero-Lorenzo, Concepción
AU  - Villa-Morales, María
AU  - Graña Castro, Osvaldo
AU  - Cobos-Fernández, María Ángeles
AU  - López-Lorenzo, José Luis
AU  - Llamas, Pilar
AU  - González-Sanchez, Laura
AU  - Sastre, Isabel
AU  - Pollan-Santamaria, Marina
AU  - Malumbres Martinez, Marcos
AU  - Santos, Javier
AU  - Fernández-Piqueras, José
PY  - 2018
DO  - 10.1186/s12885-018-4304-y
SN  - 1471-2407
UR  - http://hdl.handle.net/20.500.12105/6656
AB  - Background: Precursor T-cell lymphoblastic lymphomas (T-LBL) are rare aggressive hematological malignancies that mainly develop in children. As in other cancers, the loss of cell cycle control plays a prominent role in the pathogenesis in these...
LA  - eng
PB  - BioMed Central (BMC)
KW  - CDKN1C-E2F1-TP53 deregulation
KW  - Deregulation of miRNAs
KW  - Promoter hypermethylation
KW  - T-cell lymphoblastic lymphoma
KW  - Adolescent
KW  - Adult
KW  - Animals
KW  - Child
KW  - Cyclin-Dependent Kinase Inhibitor p57
KW  - E2F1 Transcription Factor
KW  - Epigenesis, Genetic
KW  - Female
KW  - Gene Expression Regulation, Neoplastic
KW  - Humans
KW  - Male
KW  - Mice
KW  - Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
KW  - Sequence Analysis, RNA
KW  - Signal Transduction
KW  - Tumor Suppressor Protein p53
KW  - Young Adult
TI  - RNA-Seq reveals the existence of a CDKN1C-E2F1-TP53 axis that is altered in human T-cell lymphoblastic lymphomas
TY  - research article
ER  -