TY - GEN AU - Diaz-Beya, Marina AU - Brunet, Salut AU - Nomdedeu, Josep AU - Pratcorona, Marta AU - Cordeiro, Anna AU - Gallardo, David AU - Escoda, Lourdes AU - Tormo, Mar AU - Heras, Inmaculada AU - Maria Ribera, Josep AU - Duarte, Rafael AU - Queipo de Llano, Maria Paz AU - Bargay Lleonart, Joan AU - Sampol Mayol, Antonia AU - Nomdedeu, Meritxell AU - Risueno, Ruth M AU - Hoyos, Montserrat AU - Sierra, Jorge AU - Monzo, Mariano AU - Navarro, Alfons AU - Esteve, Jordi AU - Cooperative AML Grp CETLAM PY - 2015 DO - 10.18632/oncotarget.5148 UR - http://hdl.handle.net/20.500.12105/20152 AB - Long non-coding RNAs (lncRNAs) are deregulated in several tumors, although their role in acute myeloid leukemia (AML) is mostly unknown. We have examined the expression of the lncRNA HOX antisense intergenic RNA myeloid 1 (HOTAIRM1) in 241 AML... LA - eng PB - Impact Journals Llc KW - lincRNA KW - AML KW - HOTAIRM KW - HOX KW - lncRNA KW - Disease-Free Survival KW - Disease Progression KW - Aged KW - Homeodomain Proteins KW - Young Adult KW - Adult KW - Risk Assessment KW - Humans KW - Cytogenetic Analysis KW - Phenotype KW - Male KW - Multivariate Analysis KW - Predictive Value of Tests KW - Time Factors KW - Chi-Square Distribution KW - MicroRNAs KW - Biomarkers, Tumor KW - Female KW - Risk Factors KW - Gene Expression Regulation, Neoplastic KW - Genetic Predisposition to Disease KW - Kaplan-Meier Estimate KW - RNA, Long Noncoding KW - Leukemia, Myeloid, Acute KW - Adolescent KW - Middle Aged KW - Nuclear Proteins KW - Mutation KW - Gene Expression Profiling KW - Proportional Hazards Models KW - Treatment Outcome KW - Odds Ratio TI - The lincRNA HOTAIRM1, located in the HOXA genomic region, is expressed in acute myeloid leukemia, impacts prognosis in patients in the intermediate-risk cytogenetic category, and is associated with a distinctive microRNA signature TY - research article ER -