TY  - JOUR
AU  - Anta-Felez, Berta
AU  - Perez-Rodriguez, Andrea
AU  - Castro, Judith
AU  - Garcia-Dominguez, Carlota A
AU  - Ibiza, S
AU  - Martinez, Natalia
AU  - Dura, Lara M
AU  - Hernandez, Silvia
AU  - Gragera, Teresa
AU  - Peña-Jimenez, Daniel
AU  - Yunta, M.
AU  - Zarich-Dimitrievich, Natasha
AU  - Crespo, P.
AU  - Serrador, J. M.
AU  - Santos, E.
AU  - Munoz, A.
AU  - Oliva-Martinez, Jose Luis
AU  - Rojas-Cabañeros, Jose Maria
PY  - 2016
DO  - 10.1038/cddis.2016.219
SN  - 2041-4889
UR  - http://hdl.handle.net/20.500.12105/5213
AB  - The cyclopentenone prostaglandin A(1) (PGA(1)) is an inducer of cell death in cancer cells. However, the mechanism that initiates this cytotoxic response remains elusive. Here we report that PGA(1) triggers apoptosis by a process that entails the...
LA  - eng
PB  - Nature Publishing Group
KW  - ENDOPLASMIC-RETICULUM STRESS
KW  - 15-DEOXY-DELTA(12,14)-PROSTAGLANDIN J(2)
KW  - CYCLOPENTENONE PROSTAGLANDINS
KW  - GRB2-BINDING DOMAIN
KW  - MESANGIAL CELLS
KW  - GOLGI-COMPLEX
KW  - CANCER-CELLS
KW  - DNA-BINDING
KW  - IN-VITRO
KW  - KAPPA-B
TI  - PGA(1)-induced apoptosis involves specific activation of H-Ras and N-Ras in cellular endomembranes
TY  - journal article
ER  -