TY - JOUR AU - Moreno-Càceres, J AU - Caja, L AU - Mainez, J AU - Mayoral, R AU - Martín-Sanz, P AU - Moreno-Vicente, Roberto AU - del Pozo, Miguel Angel AU - Dooley, S AU - Egea, G AU - Fabregat, I PY - 2014 DO - 10.1038/cddis.2014.294 SN - 2041-4889 UR - http://hdl.handle.net/20.500.12105/7521 AB - Transforming growth factor-beta (TGF-β) plays a dual role in hepatocytes, inducing both pro- and anti-apoptotic responses, whose balance decides cell fate. Survival signals are mediated by the epidermal growth factor receptor (EGFR) pathway, which is... LA - eng PB - Nature Publishing Group KW - ADAM Proteins KW - ADAM17 Protein KW - Animals KW - Apoptosis KW - Caveolin 1 KW - Cells, Cultured KW - Enzyme Activation KW - ErbB Receptors KW - Female KW - Hepatocytes KW - Male KW - Mice KW - Mice, Knockout KW - Phosphorylation KW - Reactive Oxygen Species KW - Signal Transduction KW - Transforming Growth Factor beta KW - Transcriptional Activation TI - Caveolin-1 is required for TGF-β-induced transactivation of the EGF receptor pathway in hepatocytes through the activation of the metalloprotease TACE/ADAM17 TY - journal article ER -