TY - JOUR AU - Hoffmann, Jedrzej AU - Richardson, Gavin AU - Haendeler, Judith AU - Altschmied, Joachim AU - Andres, Vicente AU - Spyridopoulos, Ioakim PY - 2021 DO - 10.1161/ATVBAHA.120.315695 UR - http://hdl.handle.net/20.500.12105/15207 AB - Shortened telomeres have been linked to numerous chronic diseases, most importantly coronary artery disease, but the underlying mechanisms remain ill defined. Loss-of-function mutations and deletions in telomerase both accelerate telomere shortening... LA - eng PB - American Heart Association (AHA) KW - Animals KW - Biomarkers KW - Cardiovascular Diseases KW - Clinical Trials as Topic KW - Drugs, Chinese Herbal KW - Exercise KW - Genome-Wide Association Study KW - Humans KW - Hydroxymethylglutaryl-CoA Reductase Inhibitors KW - Leukocytes KW - Mice KW - Models, Cardiovascular KW - Mutation KW - RNA KW - Telomerase KW - Telomere Homeostasis KW - Telomere Shortening TI - Telomerase as a Therapeutic Target in Cardiovascular Disease. TY - journal article ER -