TY - GEN AU - Lopez-Huertas, Maria Rosa AU - Callejas, S. AU - Abia, David AU - Mateos, Elena AU - Dopazo, A. AU - Alcamí, José AU - Coiras, Mayte PY - 2010 DO - 10.1093/nar/gkq037 SN - 0305-1048 UR - http://hdl.handle.net/20.500.12105/6965 AB - The human immunodeficiency virus type 1 (HIV-1) regulator Tat is essential for viral replication because it achieves complete elongation of viral transcripts. Tat can be released to the extracellular space and taken up by adjacent cells, exerting... LA - eng PB - Oxford University Press KW - Cell Proliferation KW - Chemotaxis KW - Computational Biology KW - Cytoskeleton KW - Exons KW - Gene Expression KW - HIV-1 KW - Humans KW - Jurkat Cells KW - Models, Molecular KW - Receptors, Cell Surface KW - Transcriptional Activation KW - tat Gene Products, Human Immunodeficiency Virus TI - Modifications in host cell cytoskeleton structure and function mediated by intracellular HIV-1 Tat protein are greatly dependent on the second coding exon TY - research article ER -