TY  - GEN
AU  - Rodríguez-Antona, C
AU  - Bort, R
AU  - Jover, R
AU  - Tindberg, N
AU  - Ingelman-Sundberg, M
AU  - Gómez-Lechón, M J
AU  - Castell, J V
PY  - 2003
DO  - 10.1124/mol.63.5.1180
SN  - 0026-895X
UR  - http://hdl.handle.net/20.500.12105/17520
AB  - Cytochrome P450 3A4 (CYP3A4) is involved in the metabolism of more than 50% of currently used therapeutic drugs, yet the mechanisms that control CYP3A4 basal expression in liver are poorly understood. Several putative binding sites for...
LA  - eng
PB  - American Society for Pharmacology and Experimental Therapeutics (ASPET)
KW  - Gene Expression Regulation, Enzymologic
KW  - Transcription Factors
KW  - Transcription, Genetic
KW  - Adenoviridae
KW  - CCAAT-Enhancer-Binding Protein-alpha
KW  - Cells, Cultured
KW  - Cytochrome P-450 CYP3A
KW  - Cytochrome P-450 Enzyme System
KW  - DNA-Binding Proteins
KW  - Enzyme Inhibitors
KW  - Genetic Vectors
KW  - Hepatocyte Nuclear Factor 3-gamma
KW  - Hepatocytes
KW  - Histone Deacetylase Inhibitors
KW  - Humans
KW  - Nuclear Proteins
KW  - Promoter Regions, Genetic
KW  - Transcriptional Activation
KW  - Transfection
TI  - Transcriptional regulation of human CYP3A4 basal expression by CCAAT enhancer-binding protein alpha and hepatocyte nuclear factor-3 gamma.
TY  - preprint
ER  -