TY - JOUR AU - Sánchez, Antonio J AU - Puerta, Carmen AU - Ballester, Sara AU - González, Paz AU - Arriaga, Angel AU - García-Merino, Antonio PY - 2005 DO - 10.1016/j.jneuroim.2005.03.024 SN - 0165-5728 UR - http://hdl.handle.net/20.500.12105/15503 AB - Rolipram suppresses experimental autoimmune encephalomyelitis (EAE) and diminishes cell infiltration of the central nervous system (CNS). In Lewis rats with EAE, rolipram reduced matrix metalloproteinase-9 (MMP-9) gene expression in lymph node cells... LA - eng PB - Elsevier KW - Experimental autoimmune encephalomyelitis KW - Rolipram KW - Nuclear factor kappa B KW - Matrix metalloproteinase-9 KW - Animals KW - Cell Movement KW - Cells, Cultured KW - Disease Models, Animal KW - Dose-Response Relationship, Drug KW - Drug Interactions KW - Electrophoretic Mobility Shift Assay KW - Encephalomyelitis, Autoimmune, Experimental KW - Gene Expression KW - Luciferases KW - Lymph Nodes KW - Lymphocytes KW - Matrix Metalloproteinase 9 KW - Myelin Basic Protein KW - NF-kappa B KW - Phosphodiesterase Inhibitors KW - RNA, Messenger KW - Rats KW - Rats, Inbred Lew KW - Reverse Transcriptase Polymerase Chain Reaction KW - Rolipram KW - Spinal Cord KW - Transfection TI - Rolipram impairs NF-kappaB activity and MMP-9 expression in experimental autoimmune encephalomyelitis TY - journal article ER -