TY - JOUR AU - Martínez, Paula AU - Sánchez-Vázquez, Raúl AU - Ferrara-Romeo, Iole AU - Serrano, Rosa AU - Flores, Juana M AU - Blasco, MA PY - 2022 DO - 10.1371/journal.pgen.1010260 UR - http://hdl.handle.net/20.500.12105/18980 AB - The shelterin protein POT1 has been found mutated in many different familial and sporadic cancers, however, no mouse models to understand the pathobiology of these mutations have been developed so far. To address the molecular mechanisms underlying... LA - eng PB - Public Library of Science (PLOS) KW - Hemangiosarcoma KW - Telomerase KW - Animals KW - Endothelial Cells KW - Fibroblasts KW - Humans KW - Li-Fraumeni Syndrome KW - Mice KW - Mutation KW - Shelterin Complex KW - Telomere KW - Telomere-Binding Proteins TI - A mouse model for Li-Fraumeni-Like Syndrome with cardiac angiosarcomas associated to POT1 mutations. TY - journal article ER -