TY - GEN AU - Alonso, Vicente AU - Escudero, Pilar AU - Fernandez-Martos, Carlos AU - Salud, Antonia AU - Mendez, Miguel AU - Gallego, Javier AU - Rodriguez, Jose-R AU - Martin-Richard, Marta AU - Fernandez-Plana, Julen AU - Manzano, Hermini AU - Mendez, Jose-Carlos AU - Zanui, Monserrat AU - Falcó, Esther AU - Gil-Raga, Mireia AU - Rojo, Federico AU - Cuatrecasas, Miriam AU - Feliu, Jaime AU - Garcia-Albeniz, Xabier AU - Maurel, Joan PY - 2018 DO - 10.1016/j.neo.2018.05.004 SN - 1476-5586 UR - https://hdl.handle.net/20.500.12105/22516 AB - INTRODUCTION: The coexpression of pIGF-1R and MMP-7 (double-positive phenotype, DP) correlates with poor overall survival (OS) in KRAS wild-type (WT) (exon 2) metastatic colorectal cancer (mCRC) patients treated with irinotecan-cetuximab in... LA - eng PB - Elsevier KW - Aged KW - Kaplan-Meier Estimate KW - Antibodies, Monoclonal KW - Humans KW - Middle Aged KW - Cetuximab KW - Matrix Metalloproteinase 7 KW - Prognosis KW - Male KW - Mutation KW - Female KW - Colorectal Neoplasms KW - Proportional Hazards Models KW - Proto-Oncogene Proteins B-raf KW - Gene Expression KW - Receptor, IGF Type 1 KW - ras Proteins TI - Coexpression of p-IGF-1R and MMP-7 Modulates Panitumumab and Cetuximab Efficacy in RAS Wild-Type Metastatic Colorectal Cancer Patients TY - research article ER -