TY - GEN AU - Vilar, Marçal AU - Sung, Tsung-Chang AU - Chen, Zhijiang AU - Garcia-Carpio, Irmina AU - Fernandez, Eva M AU - Xu, Jiqing AU - Riek, Roland AU - Lee, Kuo-Fen PY - 2014 DO - 10.1371/journal.pbio.1001918 SN - 1545-7885 UR - http://hdl.handle.net/20.500.12105/8725 AB - The p75 neurotrophin receptor, a member of the tumor necrosis factor receptor superfamily, is required as a co-receptor for the Nogo receptor (NgR) to mediate the activity of myelin-associated inhibitors such as Nogo, MAG, and OMgp. p45/NRH2/PLAIDD is... LA - eng PB - Public Library of Science (PLOS) KW - Amino Acid Sequence KW - Animals KW - Cysteine KW - HEK293 Cells KW - Humans KW - Magnetic Resonance Spectroscopy KW - Mice KW - Models, Biological KW - Models, Molecular KW - Molecular Sequence Data KW - Protein Binding KW - Protein Interaction Mapping KW - Protein Stability KW - Receptor, Nerve Growth Factor KW - Receptors, Cell Surface KW - Receptors, Nerve Growth Factor KW - Sciatic Nerve KW - Solutions KW - Structure-Activity Relationship KW - Up-Regulation KW - Protein Multimerization KW - Signal Transduction TI - Heterodimerization of p45-p75 modulates p75 signaling: structural basis and mechanism of action TY - research article ER -