TY  - JOUR
AU  - Bernard, Hugo
AU  - Teijeiro, Ana
AU  - Chaves-Pérez, Almudena
AU  - Perna, Cristian
AU  - Satish, Basanthi
AU  - Novials, Anna
AU  - Wang, Jennifer P
AU  - Djouder, Nabil
PY  - 2020
DO  - 10.1016/j.xcrm.2020.100125
UR  - http://hdl.handle.net/20.500.12105/17556
AB  - Enteroviruses are suspected to contribute to insulin-producing β cell loss and hyperglycemia-induced diabetes. However, mechanisms are not fully defined. Here, we show that coxsackievirus B type 4 (CVB4) infection in human islet-engrafted mice and in...
LA  - eng
PB  - Elsevier
KW  - Animals
KW  - Capsid Proteins
KW  - Coxsackievirus Infections
KW  - DNA (Cytosine-5-)-Methyltransferase 1
KW  - Diabetes Mellitus, Type 2
KW  - Disease Models, Animal
KW  - Enterovirus B, Human
KW  - Female
KW  - Gene Expression Regulation
KW  - Glucose
KW  - Homeodomain Proteins
KW  - Humans
KW  - Insulin-Secreting Cells
KW  - Male
KW  - Mice
KW  - Mice, Transgenic
KW  - Procainamide
KW  - Rats
KW  - Repressor Proteins
KW  - Signal Transduction
KW  - Trans-Activators
KW  - Transplantation, Heterologous
TI  - Coxsackievirus B Type 4 Infection in β Cells Downregulates the Chaperone Prefoldin URI to Induce a MODY4-like Diabetes via Pdx1 Silencing.
TY  - journal article
ER  -