TY  - GEN
AU  - Amarilla-Quintana, Sandra
AU  - Navarro, Paloma
AU  - Ramos, Alejandra
AU  - Montero-Calle, Ana Maria
AU  - Cabezas-Sainz, Pablo
AU  - Barrero, Maria
AU  - Megias Vazquez, Diego
AU  - Vilaplana-Marti, Borja
AU  - Epifano, Carolina
AU  - Gomez-Dominguez, Deborah
AU  - Hernández Martínez, Iván
AU  - Monzon-Fernandez, Sara
AU  - Cuesta de la Plaza, Isabel
AU  - Sánchez, Laura
AU  - Barderas Manchado, Rodrigo
AU  - Garcia-Donas, Jesus
AU  - Martin, Alberto
AU  - Perez de Castro, Ignacio
PY  - 2024
DO  - 10.1101/2024.07.01.601520
UR  - https://hdl.handle.net/20.500.12105/25927
AB  - FOXL2 is a transcription factor essential for sex determination and ovary development and maintenance. Mutations in this gene are implicated in syndromes involving premature ovarian failure and granulosa cell tumors (GCTs). This rare cancer accounts...
LA  - eng
KW  - Granulosa cell tumor
KW  - FOXL2
KW  - CRISPR
KW  - Rare cancer
TI  - CRISPR targeting of FOXL2 c.402C>G mutation reduces malignant phenotype in granulosa tumor cells and identifies anti-tumoral compounds
TY  - preprint
ER  -