TY - GEN AU - Cebrián-Sastre, E AU - Chiner-Oms, A AU - Torres-Pérez, R AU - Comas, I AU - Oliveros, Juan Carlos AU - Blázquez, J AU - Castañeda-García, Alfredo PY - 2023 DO - 10.1128/spectrum.01017-23 UR - http://hdl.handle.net/20.500.12105/16309 AB - Resistance to the frontline antibiotic rifampicin constitutes a challenge to the treatment and control of tuberculosis. Here, we analyzed the mutational landscape of Mycobacterium smegmatis during long-term evolution with increasing concentrations of... LA - eng PB - American Society for Microbiology (ASM) KW - DNA repair KW - Mycobacterium KW - Mycobacterium smegmatis KW - Antibiotic resistance KW - Drug resistance evolution KW - Evolution KW - Experimental evolution KW - Mutation KW - Mutation accumulation KW - Rifampicin TI - Selective Pressure by Rifampicin Modulates Mutation Rates and Evolutionary Trajectories of Mycobacterial Genomes TY - research article ER -