TY  - JOUR
AU  - Ruiz, Sergio
AU  - Lopez-Contreras, Andres J
AU  - Gabut, Mathieu
AU  - Marion, RM
AU  - Gutierrez-Martinez, Paula
AU  - Bua, Sabela
AU  - Ramirez, Oscar
AU  - Olalde, Iñigo
AU  - Rodrigo-Perez, Sara
AU  - Li, Han
AU  - Marques-Bonet, Tomas
AU  - Serrano, Manuel
AU  - Blasco, MA
AU  - Batada, Nizar N
AU  - Fernandez-Capetillo, Oscar
PY  - 2015
DO  - 10.1038/ncomms9036
SN  - 2041-1723
UR  - http://hdl.handle.net/20.500.12105/10003
AB  - The generation of induced pluripotent stem cells (iPSC) from adult somatic cells is one of the most remarkable discoveries in recent decades. However, several works have reported evidence of genomic instability in iPSC, raising concerns on their...
LA  - eng
PB  - Nature Publishing Group
KW  - Animals
KW  - Cell Line
KW  - Cell Proliferation
KW  - Cellular Reprogramming
KW  - Checkpoint Kinase 1
KW  - DNA
KW  - Fibroblasts
KW  - Gene Expression Regulation
KW  - Genomic Instability
KW  - Humans
KW  - Induced Pluripotent Stem Cells
KW  - Mice
KW  - Mice, Transgenic
KW  - Nucleic Acid Hybridization
KW  - Plasmids
KW  - Point Mutation
KW  - Protein Kinases
KW  - Stress, Physiological
TI  - Limiting replication stress during somatic cell reprogramming reduces genomic instability in induced pluripotent stem cells
TY  - journal article
ER  -