TY - JOUR AU - Schellenberg, Matthew J AU - Appel, C Denise AU - Riccio, Amanda A AU - Butler, Logan R AU - Krahn, Juno M AU - Liebermann, Jenna A AU - Cortes-Ledesma, Felipe AU - Williams, R Scott PY - 2020 DO - 10.1093/nar/gkaa318 SN - 0305-1048 UR - http://hdl.handle.net/20.500.12105/9906 AB - Tyrosyl-DNA phosphodiesterase 2 (TDP2) reverses Topoisomerase 2 DNA-protein crosslinks (TOP2-DPCs) in a direct-reversal pathway licensed by ZATTZNF451 SUMO2 E3 ligase and SUMOylation of TOP2. TDP2 also binds ubiquitin (Ub), but how Ub regulates TDP2... LA - eng PB - Oxford University Press TI - Ubiquitin stimulated reversal of topoisomerase 2 DNA-protein crosslinks by TDP2 TY - journal article ER -