TY - JOUR AU - Martin-Rojas, Tatiana AU - Mourino-Alvarez, Laura AU - Alonso-Orgaz, Sergio AU - Rosello-Lleti, Esther AU - Calvo, Enrique AU - Fernando Lopez-Almodovar, Luis AU - Rivera, Miguel AU - Padial, Luis R. AU - Lopez, Juan Antonio AU - de la Cuesta, Fernando AU - Barderas, Maria G PY - 2015 DO - 10.1038/srep17290 SN - 2045-2322 UR - http://hdl.handle.net/20.500.12105/5256 AB - Degenerative aortic stenosis (AS) is the most common worldwide cause of valve replacement. The aortic valve is a thin, complex, layered connective tissue with compartmentalized extracellular matrix (ECM) produced by specialized cell types, which... LA - eng PB - Nature Publishing Group KW - LEUCINE-RICH REPEAT KW - OSTEOBLAST-SPECIFIC FACTOR KW - TOLL-LIKE RECEPTOR-4 KW - ATHEROSCLEROTIC PLAQUES KW - INTERSTITIAL-CELLS KW - OXIDIZED LDL KW - PERIOSTIN KW - STENOSIS KW - BIGLYCAN KW - PROTEIN TI - iTRAQ proteomic analysis of extracellular matrix remodeling in aortic valve disease TY - journal article ER -