TY  - GEN
AU  - Martínez-Bosch, Neus
AU  - Fernández-Barrena, Maite G
AU  - Moreno, Mireia
AU  - Ortiz-Zapater, Elena
AU  - Munné-Collado, Jessica
AU  - Iglesias, Mar
AU  - André, Sabine
AU  - Gabius, Hans-Joachim
AU  - Hwang, Rosa F
AU  - Poirier, Françoise
AU  - Navas, Carolina
AU  - Guerra, Carmen
AU  - Fernández-Zapico, Martin E
AU  - Navarro, Pilar
PY  - 2014
DO  - 10.1158/0008-5472.CAN-13-3013
UR  - https://hdl.handle.net/20.500.12105/23068
AB  - Despite some advances, pancreatic ductal adenocarcinoma (PDAC) remains generally refractory to current treatments. Desmoplastic stroma, a consistent hallmark of PDAC, has emerged as a major source of therapeutic resistance and thus potentially...
LA  - eng
PB  - American Association for Cancer Research (AACR)
KW  - Adenocarcinoma
KW  - Animals
KW  - Carcinoma, Pancreatic Ductal
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Cell Transformation, Neoplastic
KW  - Desmoplastic Small Round Cell Tumor
KW  - Galectin 1
KW  - HEK293 Cells
KW  - Hedgehog Proteins
KW  - Humans
KW  - Mice
KW  - Neovascularization, Pathologic
KW  - Pancreatic Neoplasms
KW  - RNA Interference
KW  - RNA, Small Interfering
TI  - Galectin-1 drives pancreatic carcinogenesis through stroma remodeling and Hedgehog signaling activation.
TY  - research article
ER  -