TY  - GEN
AU  - Gomez-Mariano, Gema Maria
AU  - Matamala, Nerea
AU  - Martinez Rodríguez, Selene
AU  - Justo, Iago
AU  - Marcacuzco, Alberto
AU  - Jimenez, Carlos
AU  - Monzon-Fernandez, Sara
AU  - Cuesta de la Plaza, Isabel
AU  - Garfia, Cristina
AU  - Varela Martinez, Maria del Carmen
AU  - Huch, Meritxell
AU  - Perez de Castro, Ignacio
AU  - Posada De la Paz, Manuel
AU  - Janciauskiene, Sabina
AU  - Martinez-Delgado, Beatriz
PY  - 2020
DO  - 10.1007/s12072-019-10007-y
SN  - 1936-0533
UR  - http://hdl.handle.net/20.500.12105/9106
AB  - BACKGROUND AND AIMS: Alpha-1 antitrypsin (AAT) is a product of SERPINA1 gene mainly expressed by hepatocytes. Clinically relevant mutations in the SERPINA1 gene, such as Z (Glu342Lys), results in an expression of misfolded AAT protein having high...
LA  - eng
PB  - Springer
KW  - Alpha-1 antitrypsin deficiency
KW  - Liver
KW  - Oncostatin M
KW  - Organoids
KW  - RNA-seq
KW  - SERPINA1
TI  - Liver organoids reproduce alpha-1 antitrypsin deficiency-related liver disease
TY  - research article
ER  -