TY - GEN AU - Bermudez-Silva, Francisco J AU - Romero-Zerbo, Silvana Y AU - Haissaguerre, Magalie AU - Ruz-Maldonado, Inmaculada AU - Lhamyani, Said AU - El Bekay, Rajaa AU - Tabarin, Antoine AU - Marsicano, Giovanni AU - Cota, Daniela PY - 2016 DO - 10.1242/dmm.020750 SN - 1754-8403 UR - http://hdl.handle.net/20.500.12105/17119 AB - The endocannabinoid system (ECS) is an intercellular signalling mechanism that is present in the islets of Langerhans and plays a role in the modulation of insulin secretion and expansion of the β-cell mass. The downstream signalling pathways... LA - eng PB - The Company of Biologists KW - Cannabinoids KW - Insulin secrection KW - Rapamycin KW - Rimonabant KW - Islets KW - CB1 KW - S6K1 KW - Animales KW - Inmunotransferencia Western KW - Peso corporal KW - Endocannabinoides KW - Glucosa KW - Intolerancia a la glucosa KW - Homeostasis KW - Resistencia a la insulina KW - Células secretoras de insulina KW - Insulinas KW - Islotes pancreáticos KW - Ratones KW - Complejos multiproteicos KW - Fosforilación KW - Piperidinas KW - Pirazoles KW - Receptor cannabinoide CB1 KW - Proteína S6 ribosómica KW - Sirolimus KW - TOR serina-treonina cinasas KW - Animals KW - Blotting, Western KW - Body Weight KW - Endocannabinoids KW - Glucose KW - Glucose Intolerance KW - Homeostasis KW - Insulin Resistance KW - Insulin-Secreting Cells KW - Insulins KW - Endocrine Glands KW - Mice KW - Multiprotein Complexes KW - Phosphorylation KW - Piperidines KW - Pyrazoles KW - Receptor, Cannabinoid, CB1 KW - Ribosomal Protein S6 KW - Sirolimus KW - TOR Serine-Threonine Kinases TI - The cannabinoid CB1 receptor and mTORC1 signalling pathways interact to modulate glucose homeostasis in mice. TY - research article ER -