TY - JOUR AU - Leiva, Magdalena AU - Quintana, Juan A. AU - Ligos, Jose M. AU - Hidalgo, Andres PY - 2016 DO - 10.1038/ncomms10222 SN - 2041-1723 UR - http://hdl.handle.net/20.500.12105/5251 AB - The life-long maintenance of haematopoietic stem and progenitor cells (HSPCs) critically relies on environmental signals produced by cells that constitute the haematopoietic niche. Here we report a cell-intrinsic mechanism whereby haematopoietic cells... LA - eng PB - Nature Publishing Group KW - E-SELECTIN LIGANDS KW - TRANSFORMING GROWTH-FACTOR-BETA-1 KW - PROGENITOR CELLS KW - NICHE KW - QUIESCENCE KW - IDENTIFICATION KW - MACROPHAGES KW - NEUTROPHILS KW - HIBERNATION KW - TGF-BETA-1 TI - Haematopoietic ESL-1 enables stem cell proliferation in the bone marrow by limiting TGF beta availability TY - journal article ER -