TY - JOUR AU - Palma, Francesco AU - Affinito, Alessandra AU - Nuzzo, Silvia AU - Roscigno, Giuseppina AU - Scognamiglio, Iolanda AU - Ingenito, Francesco AU - Martinez Garcia, Maria Dolores AU - Franzese, Monica AU - Zanfardino, Mario AU - Soricelli, Andrea AU - Fiorelli, Alfonso AU - Condorelli, Gerolama AU - Quintavalle, Cristina PY - 2021 DO - 10.1038/s41417-020-00224-1 UR - http://hdl.handle.net/20.500.12105/17427 AB - Lung cancer is still the leading cause of death by cancer worldwide despite advances both in its detection and therapy. Multiple oncogenic driver alterations have been discovered, opening the prospective for new potential therapeutic targets. Among... LA - eng PB - Nature Publishing Group KW - Gene Expression Regulation, Neoplastic KW - Synthetic Lethal Mutations KW - Adenocarcinoma of Lung KW - Apoptosis KW - CDC2 Protein Kinase KW - Carcinoma, Non-Small-Cell Lung KW - Cell Movement KW - Cell Proliferation KW - Humans KW - Lung Neoplasms KW - MicroRNAs KW - Prognosis KW - Prospective Studies KW - Proto-Oncogene Proteins p21(ras) KW - Survival Rate KW - Tumor Cells, Cultured TI - miR-34c-3p targets CDK1 a synthetic lethality partner of KRAS in non-small cell lung cancer. TY - journal article ER -