TY  - JOUR
AU  - Salmón, Marina
AU  - Álvarez-Díaz, Ruth
AU  - Fustero-Torre, Coral
AU  - Brehey, Oksana
AU  - Lechuga, Carmen G
AU  - Sanclemente, Manuel
AU  - Fernández-García, Fernando
AU  - López-García, Alejandra
AU  - Rodriguez Perales, Sandra
AU  - Martín-Guijarro, María Carmen
AU  - Bousquet-Mur, Emily
AU  - Morales-Cacho, Lucía
AU  - Mulero, Francisca
AU  - Al-Shahrour, Fatima
AU  - Martinez Garcia, Maria Dolores
AU  - Domínguez, Orlando
AU  - Caleiras, Eduardo
AU  - Ortega Jimenez, Sagrario
AU  - Guerra, Carmen
AU  - Musteanu, Monica
AU  - Drosten, Matthias
AU  - Barbacid, Mariano
PY  - 2023
DO  - 10.1172/JCI164413
UR  - http://hdl.handle.net/20.500.12105/17429
AB  - KRASG12C inhibitors have revolutionized the clinical management of patients with KRASG12C-mutant lung adenocarcinoma. However, patient exposure to these inhibitors leads to the rapid onset of resistance. In this study, we have used genetically...
LA  - eng
KW  - Adenocarcinoma of Lung
KW  - Lung Neoplasms
KW  - Animals
KW  - Mice
KW  - Mutation
KW  - Oncogenes
KW  - Proto-Oncogene Proteins p21(ras)
KW  - Signal Transduction
TI  - Kras oncogene ablation prevents resistance in advanced lung adenocarcinomas.
TY  - journal article
ER  -